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An allergy can refer to several kinds of immune reactions including Type I hypersensitivity in which a person's body is hypersensitised and develops IgE type antibodies to typical proteins. When a person is hypersensitised, these substances are known as allergens. The word allergy derives from the Greek words allos meaning "other" and ergon meaning "work". Type I hypersensitivity is characterised by excessive activation of mast cells and basophils by immunoglobulin E resulting in a systemic inflammatory response that can result in symptoms as benign as a runny nose, to life-threatening anaphylactic shock and death.

Allergy is a very common disorder and more than 50 million Americans suffer from allergic diseases. Allergies are the 6th leading cause of chronic disease in the United States, costing the health care system $18 billion annually (Allergy statistics).

History


The term and concept of "allergy" was coined by a Viennese pediatrician named Clemens von Pirquet in 1906 *. He observed that the symptoms of some of his patients might have been a response to outside allergens such as dust, pollen, or certain foods. For a long time all hypersensitivities were thought to stem from the improper action of inflammatory immunoglobulin class IgE, however it soon became clear that several different mechanisms utilizing different effector molecules were responsible for the myriad of disorders previously classified as "allergies". A new four-class (now five) classification scheme was designed by P. G. H. Gell and R. R. A. Coombs. Allergy has since been kept as the name for Type I Hypersensitivity, characterised by classical IgE mediation of effects.

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Decided have wheat allergy. Added bonus; you don't eat half as much when you pay two quid for a tiny gluten free loaf.
hkolsaker (Helena Kolsaker) Sat, 07 Nov 2009 10:49:27 -0000
Decided have wheat allergy. Added bonus; you don't eat half as much when you pay two quid for a tiny gluten free loaf.
Hope For a Milk Allergy Cure at Childrens Hospital Boston | Baby ...: Hope For a Milk Allergy Cure at Childrens.. http://bit.ly/Sjrc9
2helppeople (Fred Carpenter) Sat, 07 Nov 2009 10:36:33 -0000
Hope For a Milk Allergy Cure at Childrens Hospital Boston | Baby ...: Hope For a Milk Allergy Cure at Childrens.. http://bit.ly/Sjrc9
The chicken box may just be a really bad allergy attack :S I dunno which to hope for .
myotishia (Nina Ravenwood) Sat, 07 Nov 2009 10:35:05 -0000
The chicken box may just be a really bad allergy attack :S I dunno which to hope for .
@bethanyshondark I have "allergy" 2 organized religion. Maybe coz I don't fit into any 1 of the streams.Reform has minuses but also pluses.
carolw (Carol Warady) Sat, 07 Nov 2009 10:19:11 -0000
@bethanyshondark I have "allergy" 2 organized religion. Maybe coz I don't fit into any 1 of the streams.Reform has minuses but also pluses.
Invaluable info: Allergy or Systemic Yeast Infection in Dogs | Allergies Malassezia Fungus Candida http://ow.ly/A9Mf
fun4fido (fun4fido) Sat, 07 Nov 2009 10:17:46 -0000
Invaluable info: Allergy or Systemic Yeast Infection in Dogs | Allergies Malassezia Fungus Candida http://ow.ly/A9Mf
awake. Looking like a madman ex-surfer, petting a cat called Danger and considering allergy meds.
beltranosaurus (Justin Beltran) Sat, 07 Nov 2009 10:14:19 -0000
awake. Looking like a madman ex-surfer, petting a cat called Danger and considering allergy meds.

 
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