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An allergy can refer to several kinds of immune reactions including Type I hypersensitivity in which a person's body is hypersensitised and develops IgE type antibodies to typical proteins. When a person is hypersensitised, these substances are known as allergens. The word allergy derives from the Greek words allos meaning "other" and ergon meaning "work". Type I hypersensitivity is characterised by excessive activation of mast cells and basophils by immunoglobulin E resulting in a systemic inflammatory response that can result in symptoms as benign as a runny nose, to life-threatening anaphylactic shock and death.
Allergy is a very common disorder and more than 50 million Americans suffer from allergic diseases. Allergies are the 6th leading cause of chronic disease in the United States, costing the health care system $18 billion annually (Allergy statistics).
History
The term and concept of "allergy" was coined by a Viennese pediatrician named Clemens von Pirquet in 1906 *. He observed that the symptoms of some of his patients might have been a response to outside allergens such as dust, pollen, or certain foods. For a long time all hypersensitivities were thought to stem from the improper action of inflammatory immunoglobulin class IgE, however it soon became clear that several different mechanisms utilizing different effector molecules were responsible for the myriad of disorders previously classified as "allergies". A new four-class (now five) classification scheme was designed by P. G. H. Gell and R. R. A. Coombs. Allergy has since been kept as the name for Type I Hypersensitivity, characterised by classical IgE mediation of effects. More on [ Allergy ]
Tiffani, Infamy, Blasphemy, Catastrophe, bruce lee, allergy, banana tree, sail the sea, bites the flea, crush the pea, letter D, you and me.
Cody_Dudgeon (Cody Dudgeon) Fri, 27 Nov 2009 21:37:03 -0000
Tiffani, Infamy, Blasphemy, Catastrophe, bruce lee, allergy, banana tree, sail the sea, bites the flea, crush the pea, letter D, you and me.
Just vacuumed n now I'm havin an allergy attack! Happens everytime! Was told I need a Dyson.
ms_luckyme (Chic James) Fri, 27 Nov 2009 21:33:14 -0000
Just vacuumed n now I'm havin an allergy attack! Happens everytime! Was told I need a Dyson.
How is your start to spring? Cold? Warm? Allergy-laden?
Billy_Frazier (Billy Frazier) Fri, 27 Nov 2009 21:30:10 -0000
How is your start to spring? Cold? Warm? Allergy-laden?
Oh no....I NEED allergy medicine....PLEEEASE!
Daniellewithers (Danielle Withers) Fri, 27 Nov 2009 21:25:16 -0000
Oh no....I NEED allergy medicine....PLEEEASE!
@ChimeraX Maybe just none of our patients had it or was coded under allergy syndrome. I have burning mouth syndrome which is horrid! x
Liiiiiiiiiiiizz (Liz) Fri, 27 Nov 2009 21:20:21 -0000
@ChimeraX Maybe just none of our patients had it or was coded under allergy syndrome. I have burning mouth syndrome which is horrid! x
@starangel82 No, becuase they would get hit for murder. Just take some allergy meds.
MasterXell (Timothy Burke) Fri, 27 Nov 2009 21:17:26 -0000
@starangel82 No, becuase they would get hit for murder. Just take some allergy meds.
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